Medical Weight Loss · GLP-1 · Avon, CT · TelehealthLose the fat.Keep the muscle.Keep it off.

If this sounds like you

A medical weight loss program that measures what the scale can’t. Labs, body composition and metabolic testing first, then medication when it’s right for you, and a clinician every 4 to 6 weeks.

$89 initial consultation · Program pricing set at consultation · Labs billed separately
In short

BIOGENEX medical weight loss in Avon, CT combines a 100+ biomarker panel, InBody body composition and PNOĒ metabolic testing with GLP-1 medication such as tirzepatide when clinically appropriate. Check-ins every 4 to 6 weeks adjust dose, protein and training so you lose fat and protect muscle. It starts with an $89 consultation.

01 · Why it hasn’t worked

It was never just willpower.

If you have done everything right and the weight still won’t move, something measurable is usually in the way. These are the patterns we find most often.

Insulin resistance hiding behind a “normal” A1c
Thyroid running low in the “normal” range
Perimenopause shifting fat to the middle
Low testosterone eroding muscle
A resting metabolism slower than any app assumes
Poor sleep driving hunger hormones
Years of dieting that cost muscle
Medications that promote weight gain
Biomarkers
100+
Body composition
InBody 580
Metabolism
PNOĒ RMR
Check-ins
4–6 weeks
Consult
$89
02 · What the scale hides

Same 20 pounds. Very different result.

Two people can lose the same weight on the same medication. One loses mostly fat and keeps their strength. The other loses muscle, slows their metabolism and regains. The difference is measurement, protein and training, managed every 4 to 6 weeks.

Unmanaged weight loss · illustrative
FatLean mass lost
BIOGENEX target · muscle protected
FatLean

Illustration of the goal, not a guaranteed outcome. InBody tracks your actual split at every milestone.

03 · What GLP-1 therapy does

More than appetite. A metabolic reset.

GLP-1 medications mimic gut hormones that tell your brain you are full and help your body handle sugar. In large clinical trials, the benefits reach well beyond the scale.

Quiets “food noise” and constant cravings
Fuller sooner, satisfied longer
Lower A1c, fasting glucose and insulin
Lower blood pressure and triglycerides
Less liver fat
20% fewer major cardiac events with semaglutide (SELECT)
Less sleep apnea severity with tirzepatide
Less joint load as weight comes off
04 · Battle of the GLP-1s

Semaglutide vs. Tirzepatide vs. Retatrutide: The Clinical Evidence

Three generations of the same idea, each acting on more of the hormones that regulate hunger, blood sugar and energy use. Here is what the clinical trials show.

SemaglutideTirzepatideRetatrutide
Acts onGLP-1GIP + GLP-1GIP + GLP-1 + glucagon
DosingOnce weeklyOnce weeklyOnce weekly
Pivotal trialSTEP-1 · 68 weeksSURMOUNT-1 · 72 weeksTRIUMPH-1 · 80 weeks
Average weight loss14.9% (2.4 mg)20.9% (15 mg)28.3% (12 mg)
Head-to-head13.7% in SURMOUNT-520.2% in SURMOUNT-5Not yet compared directly
Standout dataCardiovascular protection (SELECT)Sleep apnea, insulin sensitivity30.3% at 104 weeks; 28.7% in TRIUMPH-4

Results are averages from separate trials with different populations and durations, except SURMOUNT-5, which compared tirzepatide and semaglutide directly. Common side effects for all three are nausea, diarrhea and constipation, usually during dose increases. Individual results vary.

Book your $89 consult Interested in a specific GLP-1 compound and which one is best for you? Book your appointment to learn more.
05 · The program

Four pillars. Every 4 to 6 weeks.

01
Measure

100+ biomarkers including insulin, A1c, leptin, adiponectin, thyroid and sex hormones, plus InBody composition and PNOĒ resting metabolic rate.

02
Treat

GLP-1 medication when clinically appropriate, with hormone, thyroid and sleep issues addressed alongside it.

03
Protect

Protein and resistance-training targets built from your lean mass, so the weight you lose is fat.

04
Iterate

Check-ins every 4 to 6 weeks: dose, side effects, InBody and nutrition adjusted to your data, then a planned taper.

06 · The difference

BIOGENEX vs. a prescription in the mail.

BIOGENEX programOnline GLP-1 serviceDiet on your own
Labs before treatment100+ biomarkersQuestionnaireNone
Body compositionInBody at every milestoneScale weightScale weight
Metabolic testingPNOĒ resting metabolic rateNoneApp estimate
Muscle protectionProtein and training targetsRarely addressedRarely addressed
Clinician contactEvery 4–6 weeks, same clinicianAsynchronousNone
Root causesThyroid, hormones, insulin, sleepNot assessedNot assessed
07 · Getting started

Start with the data.

Step 01

Initial Consultation

$89
  • History, medications, goals and prior attempts
  • Lab and testing plan
  • In person in Avon or by telehealth
Reserve consult
Step 02

Your Program

Set at consultation
  • Medication, if appropriate, chosen with your clinician
  • Check-ins every 4 to 6 weeks
  • Baseline InBody body composition analysis, repeated quarterly
  • 20% off Fullscript supplements recommended by your clinician
  • Reduced cash-pay pricing on lab orders
  • Member-only peptide pricing
  • Members Only Community on Skool: nutrition and dietary planning, exercise programs, peptide protocols and more

Laboratory charges are billed separately.

Add-on

PNOĒ Testing

from $150
  • Resting metabolic rate and fat-burning zones
  • 20% off for Weight Loss members
About PNOĒ
Dwight “DJ” DiMartino, APRN, FNP-C
Dwight “DJ” DiMartino, APRN, FNP-C
Founder · Lead Clinician

Functional nutrition, metabolic medicine and hormone optimization in one clinician, who looks at the whole system instead of a single number on the scale.

“When I first started working with him, I wasn’t feeling my best, and he took the time to understand what was really going on rather than just treating symptoms.”
Tai B.
“For me being in my 40s and feeling like I’m in my 20s was very important… If you are serious about your health and want real service look no further.”
Igor C.
08 · Weight loss questions

Straight answers on GLP-1.

Can’t find your question? Call 959-204-5375 or ask at your consultation.

How does the BIOGENEX medical weight loss program work?

It starts with an $89 consultation and a 100+ biomarker panel, InBody body composition and, where useful, PNOĒ resting metabolic rate testing. Your clinician then builds a plan that may include GLP-1 medication such as tirzepatide when clinically appropriate, protein and training targets to protect muscle, and check-ins every 4 to 6 weeks to adjust dose and nutrition.

What is a GLP-1 medication?

GLP-1 receptor agonists such as semaglutide, and dual GIP/GLP-1 agonists such as tirzepatide, reduce appetite, slow stomach emptying and improve blood sugar control. They are prescription medications that require clinical evaluation and monitoring.

Which GLP-1 medications does BIOGENEX prescribe?

When clinically appropriate, BIOGENEX prescribes FDA-approved GLP-1 medication such as tirzepatide. The right choice depends on your history, labs, goals, prior response and how you tolerate the medication, and the dose is adjusted at each check-in. If you want to learn more about a specific GLP-1 compound and which one is best for you, book your $89 consultation.

Semaglutide or tirzepatide: which works better?

Both work. Tirzepatide acts on two hormone receptors (GIP and GLP-1) and produced more weight loss in the head-to-head SURMOUNT-5 trial: an average of 20.2% of body weight at 72 weeks, versus 13.7% with semaglutide. Semaglutide has the largest cardiovascular outcome data, including a 20% reduction in major cardiac events in the SELECT trial. Your clinician weighs both against your history and goals.

What is retatrutide?

Retatrutide is a once-weekly triple agonist that acts on GIP, GLP-1 and glucagon receptors. In the phase 3 TRIUMPH-1 trial, adults without diabetes lost an average of 28.3% of body weight at 80 weeks on the 12 mg dose, and 30.3% at 104 weeks in an extension group. It is still investigational and in clinical trials. Ask about it at your consultation and we will walk you through the latest data.

Will I lose muscle on a GLP-1?

Some of the weight lost on any calorie deficit can come from lean mass. BIOGENEX tracks body composition with InBody at every milestone and sets protein and resistance-training targets so the weight you lose is mostly fat.

Why test hormones and thyroid for weight loss?

Thyroid dysfunction, insulin resistance, low testosterone, perimenopause and high cortisol can all make weight loss harder. Testing 100+ biomarkers first means the plan addresses the cause, not only appetite.

How much does medical weight loss cost at BIOGENEX?

The initial consultation is $89. Program pricing depends on the medication and plan chosen and is set at your consultation. Laboratory charges are billed separately. Weight loss members receive 20% off PNOĒ metabolic testing, which starts at $150.

How often are check-ins?

Clinician check-ins happen every 4 to 6 weeks during active treatment, with dose, side effects, InBody results and nutrition reviewed each time.

What happens when I stop the medication?

Weight regain is common after stopping GLP-1 medication without a plan. BIOGENEX uses the treatment period to build muscle, habits and metabolic data, then tapers and adjusts with you rather than stopping abruptly.

Is the weight loss program available by telehealth?

Yes. Consultations and check-ins are available by telehealth across Connecticut and in other states where the treating clinician is licensed. InBody and PNOĒ testing are done in person at 51 East Main St, Avon, CT.

How is this different from an online GLP-1 service?

Online services usually send a prescription after a questionnaire. BIOGENEX starts with labs and body composition, sees you every 4 to 6 weeks, protects muscle, and treats the hormonal and metabolic causes behind weight gain.

Where we treat

Medical weight loss in Avon, CT and across Connecticut.

BIOGENEX is at 51 East Main St, Avon, CT 06001, in the Farmington Valley, about 20 minutes from Hartford and West Hartford. Patients come in person from across Hartford County and Fairfield County. Telehealth care is available throughout Connecticut and in other states where the treating clinician is licensed; labs are drawn at a local site near you.

AvonWest HartfordFarmingtonSimsburyCantonGlastonburySouthingtonNewingtonBristolCheshirePlainvilleHamdenWallingfordNew HavenFairfield CountyTelehealth across CT
Start hereReserve $89 consultIn person in Avon or by telehealth. Response within 24 hours. Call the clinic959-204-5375info@biogenexct.com
Reserve $89 ConsultFree Lab Trial