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The Apex.

Elite clinician-led precision medicine. Deep-dive biomarker analysis engineered for peak human performance.

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51 East Main St · Avon, CT 06001
biogenexct.com · Telehealth in Eligible States
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Protocol 07 · PNOĒ Metabolic Testing

Stop Training
on Guesswork.

Breath-by-breath metabolic analysis. A single 20-minute test reveals your VO2 Max, Zone 2 threshold, anaerobic ceiling, resting metabolic rate, and lung efficiency. This is the data your training and nutrition have been operating without. Testing starts at $150.

Test Time
20 Minutes
Starts At
$150
Measures
VO2 Max · Zone 2 · RMR
Output
Your Exact Zones
Athlete performing a PNOĒ breath-by-breath metabolic test wearing the analysis mask at BIOGENEX
A PNOĒ metabolic test in progress — every breath analyzed to map your true training zones.
The Signal

Your Zones Are
a Guess. Until Now.

Your watch estimates your heart rate zones from a formula. Your calorie targets come from a generic equation. Your “Zone 2” is a number someone assigned to your age, not your physiology. You have been training and eating on assumptions.

PNOĒ measures the truth. By analyzing every breath you take during a short, guided test, it reveals exactly how your body produces and uses energy, so your training and nutrition can finally be calibrated to you.

Signal 01
Wrong Training Zones
Heart-rate zones estimated by formula that may sit nowhere near your true metabolic thresholds.
Signal 02
Guessed Calorie Needs
A resting metabolic rate assumed from an equation rather than measured, undermining every nutrition plan.
Signal 03
Unknown VO2 Max
The single strongest fitness and longevity marker, left unmeasured and unimproved.
Signal 04
Inefficient Fat Burning
No clarity on the intensity at which your body actually burns fat versus carbohydrate.
Signal 05
Untested Anaerobic Ceiling
No data on where your performance breaks down, so training never targets it precisely.
Signal 06
Plateaued Results
Effort that no longer produces change because it is aimed at the wrong zones.
Where Standard Care Fails

Estimates Are Not
Measurements.

Calibrated to You, Not a Formula.

Generic fitness advice assumes everyone’s physiology is the same. It is not. Two people the same age and weight can have completely different metabolic thresholds, fat-burning zones, and resting metabolic rates. Training both to the same formula wastes the effort of at least one of them.

PNOĒ replaces estimation with measurement. In 20 minutes of breath-by-breath analysis we map your VO2 Max, Zone 2 threshold, anaerobic ceiling, resting metabolic rate, and lung efficiency. Your clinician then calibrates training intensity and nutrition to your actual numbers. This is performance medicine, not a wearable’s best guess.

20
Minutes to map your metabolism
$150
Where PNOĒ testing starts
VO2
Max, a top longevity marker, measured
0
Guesswork in your zones
Wattbike Atom precision performance bike used for PNOĒ metabolic testing at BIOGENEX
The Wattbike Atom — the precision ergometer you ride during the graded PNOĒ test.
The BIOGENEX Protocol

How We
Read Your Engine.

01
Breath-by-Breath Test
A guided 20-minute assessment measures oxygen consumption and output breath by breath to reveal how your body produces energy.
02
Map Your Zones
We define your true Zone 2, anaerobic threshold, VO2 Max, fat-burning intensity, and resting metabolic rate, calibrated to your physiology.
03
Calibrate and Apply
Your clinician translates the data into precise training intensities and nutrition targets, then re-tests to confirm progress.
The Instrument · Body Composition

InBody 580.
Muscle, Fat & Fluid, Measured.

A bathroom scale gives you one number that hides everything that matters. The InBody 580 is a medical-grade body composition analyzer that uses direct segmental multi-frequency bioelectrical impedance to break your body weight into its real components in about 60 seconds — no calipers, no pinching, no estimates.

We run it alongside your PNOĒ metabolic test and your 100+ biomarker panel, so muscle, fat, metabolic rate, and hydration are tracked as one system and re-measured over time to prove your protocol is actually working.

Test Time
~60 Seconds
Method
Segmental MF-BIA
Reads
Muscle · Fat · Water
Role
Tracked Every Re-Test
InBody 580 medical-grade body composition analyzer at BIOGENEX
The InBody 580 in the BIOGENEX lab — muscle, fat, and fluid measured in about 60 seconds.
Measures 01
Skeletal Muscle Mass
Segmental lean mass for each arm, each leg, and your trunk. Muscle drives strength, metabolic rate, and healthy aging — and it is the first thing we protect on a weight-loss protocol so you lose fat, not muscle.
Measures 02
Body Fat & Visceral Fat
Total body fat percentage plus the visceral fat wrapped around your organs — the fat most tied to metabolic and cardiovascular risk. We track it to confirm fat loss is real and coming from the right places.
Measures 03
Metabolic Health & BMR
Your Basal Metabolic Rate and phase angle, a cellular-health marker tied to muscle quality. BMR sets your true calorie needs, so nutrition targets are calibrated to your body instead of a generic formula.
Measures 04
Hydration & Fluid Balance
Total body water split into intracellular and extracellular compartments and reported as the ECW/TBW ratio. It flags dehydration, inflammation, and fluid shifts, and tells us whether a change on the scale is fat, muscle, or water.
Questions, Answered

PNOĒ Testing, Answered.

What does PNOĒ actually measure?

It measures your oxygen consumption and carbon dioxide output breath by breath to determine your VO2 Max, metabolic thresholds, fat-burning zones, resting metabolic rate, and breathing efficiency.

Who is this for?

Anyone serious about training, body composition, or longevity. From competitive athletes to executives optimizing health, the test removes guesswork from how you train and eat.

How is this better than my smartwatch?

Wearables estimate zones from formulas. PNOĒ measures your actual physiology directly, so your zones and calorie needs are precise rather than approximated.

How much does it cost?

PNOĒ testing starts at $150 as a separate tier and can be integrated into your broader performance protocol.

Begin Your Protocol

Measure the Engine.
Then Tune It.

Book your PNOĒ assessment. Twenty minutes replaces a lifetime of training on guesswork.

Avon, CT · Telehealth in Eligible States · Response Within 24 Hrs